Physiological and Behavioral Responses to Optogenetic Stimulation of PKD2L1+ Type III Taste Cells

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Sour Taste Responses in Mice Lacking PKD Channels

BACKGROUND The polycystic kidney disease-like ion channel PKD2L1 and its associated partner PKD1L3 are potential candidates for sour taste receptors. PKD2L1 is expressed in type III taste cells that respond to sour stimuli and genetic elimination of cells expressing PKD2L1 substantially reduces chorda tympani nerve responses to sour taste stimuli. However, the contribution of PKD2L1 and PKD1L3 ...

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ژورنال

عنوان ژورنال: eneuro

سال: 2019

ISSN: 2373-2822

DOI: 10.1523/eneuro.0107-19.2019